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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '443e911a9506f8b642a2059ea607e335ce915f95b2acdeb15f6dc2f1b15e9695' 
  AND token = 'cbZ2pTLzTgHxsaPl1VpdvbbSjFiyFHOTGV2BoQxOGWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}