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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4998ff2f0ff208882838bdbf2931aa4e3df1b780695ce37be425eb04e1e1992b' 
  AND token = 'wMaWFU+bq8Bm/LDxM6zenwyftXk3yuyOhlM+c+EbqWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}