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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '72bbf37ddd316d70e4019e8295bc09223ee336ed8e1c9211a39e43a2cca8174d' 
  AND token = '2zYBoAuWKB2opTaBVPgK5ASM1gI4bL3mIQKXaogz8kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}