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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '66c07323abb7b610ca44eca705b4fc8767014a5e9197e14d55ee4adaa3f0be21' 
  AND token = 'twcQ+usLlaXXa6NzWhP0Q6bivW0vGlUFRLwnYQ8hWe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}