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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2ef1029343f3c1d0a4dedf77c2e1b87a0b4f25f9a2f06a960effb43f678613bd' 
  AND token = 'T2DdU9toP0rg0XwZXZ6u73lWVV6AL2PbZYsdGw8lKqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}