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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4230c78a19e6d8e559b3109a6b4eed460c997d8e98fb76a570697e4c4bb4e395' 
  AND token = 'hE31fhx5MketH618iSEGLKTr0PMqozLA2k7wgaOKs14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}