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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cddd0c951cccb35df80a9591119bb32356f18f07abf3aaa45db78f45c3a21aa9' 
  AND token = 'y64X1Oq2WWyzWhvq1kpKMW519xNG1V6ssdZldaZGrh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}