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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21ed37878a1a8c27942c83622156278660293debe533464ea5841662081c2ef5' 
  AND token = 'Nxxe0JnnkUn+/iSfqya7A7SdQyB8n5RW/i40kMS5ITI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}