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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a5fffb52c4e36dd0903d7ca409c8c89ee26b247890be7b5523bec0c278f96529' 
  AND token = 'KqesbGkGuXGyQIfReADiqLCF2yhd7j9y25dgWBQ9BhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}