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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '15a6ff707227d43a4a91b38372519c1ac16a8dfad1496e752fdf65b8afa52c96' 
  AND token = 'ASPy2f0PHk5OewlTrUQtpWlMrL2jDbSvpTGZPwGFKkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}