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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd0a5144df734091f445dd135134e5ee1e51db7b2d45b8c7a98e600e553c9bea2' 
  AND token = 'r3kWV7BWM+bHBtiOjjPbjvQPtCKhl+3CuKkQio9Vea0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}