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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21941a95902349a6b6206cab08accc71dbb9ff80144bdd95be17243d0deaffe9' 
  AND token = 'ZIcywLzP+Cjba8sk1cuPf0TQvntOoDA6Sr3HPC+nRaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}