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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ef4f24fd96a39aae3bd2cf21647512f91555a716c43b3852b71708245343f414' 
  AND token = 'sol0pCZx2550yje18S442N06ojNcm/qWGMaJmzOUMro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}