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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '410ec20074a672613a595c44686c3e92b46038a87ad2b8c1f53df5579a005c01' 
  AND token = '82ZXEEeO1HKFfd/480fOST0e5/F/tsJMvVlImGa0E/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}