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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3c4aa72bfceb6662aa341d856da3bc0a0963b190303dc178e318b89abae4c7e4' 
  AND token = 'kUxTA2jKWBGG90GBjdFpBVQ00hXKcOCFlFcxhTyIYf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}