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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '72bb66869ae08218731b1fd806351bb5fe91b814cc664c4d9f457ba87337c3a8' 
  AND token = 'DOXQHvAoLV2gmDVmXMx4DUTO8sfmFEMMbEQk/8VHmm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}