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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '72545aed217c65823c160bde0bef0c522283f112e66ddd8210e82fbda5ab18de' 
  AND token = '+48Sl5OPIrAt1LiFrX8264OttIwD8vhmgU93+arZnu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}