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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '61722202f2b07b7667209653eb59546921d21000a8da3c2d6afcfea8dfd03a04' 
  AND token = '/UcE9dBDweLMgALz5N8y1UJmqNn4HCFWLciXpBLBDoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}