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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c4ea0721307ae8af52115828ba9534a70778515ff1aa26cdc88523f78e182307' 
  AND token = '4BAanxZgxcYW2lZcO977/tqPLaAcCpsNIPME4AoE6ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}