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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '16a54b0c8cb40009b38b1211706c0d1c5596027ad7376d0f5464149eff5f2f16' 
  AND token = 'vL1CPHPYS6FEnLBl3P0CickbEMw7gwPjmyL7syZxtIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}