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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4333651bf3630471ec109e72d42cb66035d6e45b0b11de139e1417473d200f6e' 
  AND token = 'ZDoXKtJIYFgpeiWY4VaEOreQf/kqIM5oxGi0UomRtRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}