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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '527a7a1e8115265f1abdca708cb8ce7e225e01530445d47327fd32edc5b09df4' 
  AND token = 'NndhCJhW6kVWq2GpeLiEMxJhuuP/jXJSO7PyCMqREdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}